Drug Sapropterin [ DR10000000360 ]
Summary
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Synonym type
Generic Names;Trade Names;synonym
Synonym
(6R)-L-erythro-5678-tetrahydrobiopterin (6R)-L-erythro-tetrahydrobiopterin (鈭?-(6R)-2-amino-6-((1R2S)-12-dihydroxypropyl)-5678-tetrahydro-4(3H)-pteridinone 2-Amino-6-(12-dihydroxypropyl)-5678-tetrahydoro-4(1H)-pteridinone 5678 Tetrahydrobiopterin 5678-Tetrahydrobiopterin 6R-5678-tetrahydrobiopterin 6R-BH4 6R-L-5678-tetrahydrobiopterin BH4 Dapropterin Kuvan Phenoptin R-THBP Sapropterin Sapropterina Tetrahydrobiopterin sapropterin sapropterinum
Xref
DrugBank: DB00360   PharmGKB: PA161990676  
CAS
62989-33-7
Formular
C9H15N5O3
PubChem CID
CID 44257
UNII
EGX657432I
ATC code
A16AX07
Drug Type
small molecule
Drug status
approved
Source
PharmGKB;Drugbank
Classification
Drug Name Synonyms Formular PubChem_CID ATC code Drug Type Drug Status Relation
Protein name Summary Xref PMID Relation