Pathway
Non-homologous end joining
[ PW0000152 ]
- Summary
- (From http://en.wikipedia.org/wiki/Non-homologous_end_joining) Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. NHEJ is referred to as "non-homologous" because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a homologous sequence to guide repair. NHEJ is evolutionarily conserved throughout all kingdoms of life and is the predominant double-strand break repair pathway in mammalian cells.
- Source
- WikiPathways
- Pathway Ontology
- non-homologous end joining pathway of double-strand break repair
Classification
Pathway
| Gene Symbol | Genomic Location | Type of Gene | Protein name | Ensembl RNA | Refseq RNA | Relation |
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